Bromocriptine mesylate

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter.

Bromocriptine (CB-154) is a dopamine D2 receptor agonist (Ki=3 nM) and and various serotonin receptors, also inhibits the release of glutamate by reversing the glutamate GLT1 transporter; decreases body fat in animal and human models and increases lean muscle mass, improves glucose intolerance and insulin resistance, and reduces triglycerides and free fatty acids; also induces apoptosis and decreases colony formation in AML cells, shows synergy with standard agents and selectivity for the leukemic cell; reduces hyperphagia and adiposity in rats with diet-induced obesity.Diabetes Approved

CB-154

GPCR/G Protein

Dopamine Receptor

Dopamine Receptor

Metabolic Disease

Diabetes

22260-51-1

750.70

C33H44BrN5O8S

>98% (HPLC)

DMSO: ≥ 30 mg/mL

O=C([C@H](C=C12)CN(C)[C@]2([H])CC3=C(Br)NC4=C3C1=CC=C4)N[C@@](O5)(C(C)C)C(N6[C@]5(O)[C@@](CCC7)([H])N7C([C@@H]6CC(C)C)=O)=O.CS(=O)(O)=O

Ergotaman-3',6',18-trione, 2-bromo-12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5α)-, methanesulfonate (1:1)

(-20℃)

With Ice Pack

≥ 2 years